Long-read sequencing is a Next-Generation Sequencing technique that allows for longer DNA or RNA fragments to be sequenced without fragmentation, like in short-read sequencing. Long-read sequencing can accommodate up to 20,000 base pairs of a DNA\/RNA strand without being previously fragmented. Unbroken long-reads increase the detection of complex structural variants, such as large inversions, deletions, or translocations. Long-reads also help resolve repetitive and complex regions, like centromeric regions or long repeats.<\/p>\n","protected":false},"excerpt":{"rendered":"
Long-read sequencing is a Next-Generation Sequencing technique that allows for longer DNA or RNA fragments to be sequenced without fragmentation, like in short-read sequencing. Long-read sequencing can accommodate up to 20,000 base pairs of a DNA\/RNA strand without being previously fragmented. Unbroken long-reads increase the detection of complex structural variants, such as large inversions, deletions, or translocations. Long-reads also help resolve repetitive and complex regions, like centromeric regions or long repeats.<\/p>\n